CBD can facilitate the treatment of pain, both when used individually and when utilized with other cannabis compounds. When CBD is used separately, it can help conditions like inflammatory pain, including pain resulting from arthritis and injuries.
According to one animal study on arthritis pain, the topical utilization of CBD prompted a decrease in irritation and pain. Another animal study found that CBD diminishes neuropathic pain by suppressing chronic inflammation.
CBD doesn’t legitimately tie to the receptors of the endocannabinoid system. However, it works by tweaking the impacts of the endocannabinoids (the cannabinoids which occur naturally in our bodies), also functioning as a CB1 receptor antagonist.
CBD helps intercede pain by diminishing inflammation, mainly by hindering inflammatory mediators. CBD can also potentiate glycine receptors, which can directly regulate pain at the spinal level. This also relieves neuropathic and inflammatory pain.
THC has properties that can treat pain, and research shows that THC can relieve central and neuropathic pain. THC can also reduce different types of pain, such as pain related to cancer, AIDS, and fibromyalgia.
THC functions mainly as a halfway CB1 receptor agonist, which implies that it will tie partially to these receptors, which prompt the leads to different effects when THC is available with other CB1 agonists, antagonists, or both. THC can also affect the serotonergic, dopaminergic, and glutamatergic systems – an activity which may add to its pain-diminishing advantages. Furthermore, THC has been found to have anti-inflammatory effects.